Tirzepatide dosage
Tirzepatide comes in 10 mg and 20 mg vials. Pick your vial to see exactly how much bacteriostatic water to add and how many insulin units to draw. Tirzepatide is the prescription drug Mounjaro/Zepbound, dosed once weekly per its FDA label (2.5 mg start, max 15 mg). The approved product is a metered pen with no reconstitution; the math here is for research vials only.
- At 1 mL water
- 10 mg/mL
- Per unit
- 100 mcg
- At 1 mL water
- 20 mg/mL
- Per unit
- 200 mcg
Calculate for your vial
Enter the mg on your Tirzepatide vial, the bacteriostatic water you added, and your target dose — it works out the exact units to draw on a U-100 insulin syringe, for whatever you personally have.
Reconstitution Calculator
Check the decimal. A misplaced decimal point here is a 10× dosing error. Re-read every number, and confirm your dose with a licensed clinician before you draw.
Educational only — not a dosing recommendation. This tool does the measurement math; it does not tell you what to take. On a U-100 insulin syringe, 100 units = 1 mL.
Dosing schedule
Tirzepatide · fixed weekly step-up schedule
A fixed weekly titration ladder. Heavier individuals more often titrate toward the 10–15 mg maintenance doses (the largest weight loss), while lighter responders can hold at 5 mg.
- 12.5 mg/wkWeeks 1–4Starting dose (initiation only)
- 25 mg/wkWeeks 5–8Maintenance dose
- 37.5 mg/wkWeeks 9–12Step-up
- 410 mg/wkWeeks 13–16Maintenance dose
- 512.5 mg/wkWeeks 17–20Step-up
- 615 mg/wkWeek 21+Maintenance / max
Everyone starts at 2.5 mg and increases in 2.5 mg steps no sooner than every 4 weeks — the approved maintenance doses are 5, 10, or 15 mg (7.5 and 12.5 are step-ups, not endpoints). Heavier people more commonly titrate toward 10–15 mg; lighter responders can hold at 5 mg. The dose is chosen by tolerability and response under medical supervision, not from a weight calculation.
Source: FDA label — Zepbound® (tirzepatide). Educational only — not medical advice and not a dosing recommendation. Any dosing decision belongs with a licensed clinician.
Reconstitution figures are deterministic measurement math. WikiPeps is a community reference and sells injection supplies only — never peptides. Nothing here is medical advice.