Epithalon is a synthetic tetrapeptide made of four amino acids — alanine, glutamic acid, aspartic acid, and glycine (Ala-Glu-Asp-Gly). It was developed by Russian researchers as a synthetic version of the active fragment of epithalamin, an extract of the pineal gland. It is a research chemical, not an approved medicine.

What is Epithalon studied for?

Most Epithalon research focuses on aging: activation of the enzyme telomerase, lengthening of telomeres in cell cultures, restoration of melatonin rhythms, and antioxidant effects. Much of this work is laboratory or animal research from a single research group, and human data are very limited.

Is Epithalon FDA-approved?

No. Epithalon is not approved by the FDA for any condition and is not part of any approved drug product. It is sold only as a research chemical labeled 'for research use only.' It has not been evaluated in large Western clinical trials.

Does Epithalon actually extend telomeres or lifespan in humans?

This is not established. Telomere and telomerase effects have been reported mainly in cell cultures, and lifespan or mortality findings come largely from older Russian studies that do not meet modern randomized-trial standards. There is no reliable proof of an anti-aging benefit in humans.

What are the risks of Epithalon?

Human safety data are very limited, so the risks are largely uncharacterized. General concerns with any reconstituted research peptide include injection-related infection, contamination or mislabeling of unregulated products, and unknown long-term effects. Anyone considering it should talk to a licensed clinician first.

Epithalon is not a controlled substance in the U.S., but it is also not an approved drug or dietary supplement. It is sold as a research chemical. It has been nominated as a bulk drug substance for possible use in pharmacy compounding and is under FDA advisory-committee review; it is not currently approved for compounding. Legal status differs by country, so check local rules.

How is research-grade Epithalon stored and prepared?

It typically ships as a lyophilized powder that must be kept cold and reconstituted with a sterile diluent before any laboratory use. WikiPeps describes the general handling process for education only and does not publish human dosing protocols.

Aging · Dosage

Epithalon dosage

Epithalon comes in 10 mg and 30 mg vials. Pick your vial to see exactly how much bacteriostatic water to add and how many insulin units to draw. Reconstitution math and unit conversions for the 10 mg and 30 mg vials. Epithalon has very limited human data and no validated dose; the short-course figures shown are community-reported and anecdotal.

10mg

At 2 mL water: 5 mg/mL
Per unit: 50 mcg

See the 10 mg card

30mg

At 2 mL water: 15 mg/mL
Per unit: 150 mcg

See the 30 mg card

Calculate for your vial

Enter the mg on your Epithalon vial, the bacteriostatic water you added, and your target dose — it works out the exact units to draw on a U-100 insulin syringe, for whatever you personally have.

Reconstitution Calculator

200 units exceeds one U-100 syringe — add more water to lower the concentration.

Units to draw (U-100)200units

Volume to draw2mL

Concentration5mg/mL

Per insulin unit50mcg

Doses per vial1doses

Check the decimal. A misplaced decimal point here is a 10× dosing error. Re-read every number, and confirm your dose with a licensed clinician before you draw.

Educational only — not a dosing recommendation. This tool does the measurement math; it does not tell you what to take. On a U-100 insulin syringe, 100 units = 1 mL.

Reconstitution figures are deterministic measurement math. WikiPeps is a community reference and sells injection supplies only — never peptides. Nothing here is medical advice.