MOTS-c
How to reconstitute the 20 mg vial and convert any target dose into insulin units. Reconstitution math and unit conversions for the 10 mg and 20 mg vials. MOTS-c has no validated human dose; the usage pattern shown is community-reported and anecdotal.
No validated human dose. MOTS-c is a research-use peptide with no FDA-approved dose. The reconstitution math below is exact measurement — a calculator, not advice. Any usage figures are community-reported and clearly labeled, and none of this is medical advice.
Calculate for your vial
Enter the mg on your MOTS-c vial, the bacteriostatic water you added, and your target dose — it works out the exact units to draw on a U-100 insulin syringe, for whatever you personally have.
Reconstitution Calculator
Check the decimal. A misplaced decimal point here is a 10× dosing error. Re-read every number, and confirm your dose with a licensed clinician before you draw.
Educational only — not a dosing recommendation. This tool does the measurement math; it does not tell you what to take. On a U-100 insulin syringe, 100 units = 1 mL.
Personalize by body weight & height
MOTS-c · tailored to you
Some community write-ups scale MOTS-c by body weight (~2–10 mcg per lb), so heavier users take more — but this is anecdotal, with no human trial behind it.
Enter your body weight above to see the research-derived range.
Typical flat community dose: 200 mcg – 1 mg per injection.
The per-weight figure (~2–10 mcg/lb) is community-reported and anecdotal — there is no human trial establishing a weight-based MOTS-c dose. An alternative flat community ladder titrates ~200 → 1000 mcg/day.
Source: Community-reported / anecdotal — ~2–10 mcg per lb; no validated human dose. Educational only — not medical advice and not a dosing recommendation. Any dosing decision belongs with a licensed clinician.
1 · Find your dose
Pick what you're using MOTS-c for and how much bacteriostatic water you added — this pulls out the exact units to draw and how often people report using it.
to draw 2.5 mg–5 mg at 2 mL water
10 mg/mL · 100 mcg per unit
- How often
- 2–3× weekly
- Cycle
- ~4–8 weeks, often cycled on/off
Community-reported and anecdotal (~5–10 mg per week split across 2–3 injections). No completed human clinical trials exist for native MOTS-c; not a recommendation and not medical advice.
2 · Reconstitute it cleanly, step by step
How to turn the 20 mg powder into a measured liquid with clean, sterile technique. More water means each insulin unit holds less peptide — easier to measure small amounts accurately.
1Swab the stoppers
Wipe the rubber top of each vial with an alcohol pad and let it air-dry.
2Draw the water
Pull your bacteriostatic water up into the insulin syringe.
3Reconstitute
Inject it slowly down the inside wall of the peptide vial — never straight onto the powder.
4Swirl to dissolve
Gently swirl until the powder fully dissolves into a clear liquid. Never shake.
5Equalize, then draw
To draw a dose: push in an equal amount of air first to equalize the pressure, then pull your dose.
- 1
Swab both tops
Wipe the rubber top of the bacteriostatic-water vial and the MOTS-c vial stopper with a fresh alcohol pad, and let them air-dry. Never touch the needle or the stoppers after wiping.
Alcohol swab · let dry - 2
Draw the water
First pull 2 mL of air into the syringe and inject it into the bacteriostatic-water vial to equalize the pressure, then draw your 2 mL of water back out. Inject it into the MOTS-c vial down the inside glass wall, not onto the powder.
2 mL BAC water - 3
Swirl, don't shake
Gently swirl the 20 mg vial until the powder fully dissolves into a clear liquid. Never shake — shaking can damage the peptide and foam the solution.
Swirl, don't shake - 4
Know your strength
The vial is now 10 mg/mL. Each unit on a U-100 syringe holds about 100 mcg.
10 mg/mL - 5
Re-swab & draw your dose
Wipe the stopper again. With a fresh insulin syringe, pull back 25 units of air and inject it into the vial to equalize the pressure, then draw 25 units (0.25 mL) for a 2.5 mg dose.
25 units - 6
Store it right
Keep the mixed vial in the fridge, away from light. Use a new sterile syringe every time, never share, and drop used sharps in a proper container.
Refrigerate · fresh needle
What each water volume gives you:
3 · Full units reference
Every bacteriostatic-water volume (rows) against every target dose (columns) — each cell is the U-100 units and the exact draw in mL. The highlighted row is the easiest volume to measure.
| BAC water | Concentration | Per unit | 1 mg | 2.5 mg | 5 mg |
|---|---|---|---|---|---|
| 1 mL | 20 mg/mL | 200 mcg | 5u0.05 mL | 12.5u0.125 mL | 25u0.25 mL |
| 2 mLeasy pick | 10 mg/mL | 100 mcg | 10u0.1 mL | 25u0.25 mL | 50u0.5 mL |
| 3 mL | 6.67 mg/mL | 66.67 mcg | 15u0.15 mL | 37.5u0.375 mL | 75u0.75 mL |
4 · Everyday usage
MOTS-c is a research peptide with no completed human trials and no validated dose. The pattern below is community-reported only.
Metabolic support (community)
Community-reported · anecdotalA weekly amount people commonly split across a few subcutaneous injections, usually in cycles.
- Reported amount
- 2.5 mg–5 mg≈ 25–50 units @ 2 mL
- Frequency
- 2–3× weekly
- Cycle
- ~4–8 weeks, often cycled on/off
Community-reported and anecdotal (~5–10 mg per week split across 2–3 injections). No completed human clinical trials exist for native MOTS-c; not a recommendation and not medical advice.
Frequently asked questions
How many insulin units is 1 mg of MOTS-c from a 20 mg vial?
- Reconstituting a 20 mg vial with 2 mL of bacteriostatic water gives 10 mg/mL — about 100 mcg per unit. Drawing 1 mg is 0.1 mL, or 10 units on a U-100 insulin syringe. This is measurement math, not a dose recommendation.
How many insulin units is 2.5 mg of MOTS-c from a 20 mg vial?
- Reconstituting a 20 mg vial with 2 mL of bacteriostatic water gives 10 mg/mL — about 100 mcg per unit. Drawing 2.5 mg is 0.25 mL, or 25 units on a U-100 insulin syringe. This is measurement math, not a dose recommendation.
Is MOTS-c proven in humans?
- No. MOTS-c is a mitochondrial-derived peptide studied mostly in cells and animals; there are no completed human clinical trials for native MOTS-c and no FDA approval. The figures here are community-reported and anecdotal. Dosing decisions belong with a licensed clinician.
WikiPeps is a community reference. Reconstitution figures are deterministic measurement math; usage figures are sourced and labeled. Nothing here is medical advice, a recommendation, or an offer to sell peptides — dosing decisions belong with a licensed clinician.