TB-500 is a synthetic peptide based on a fragment of Thymosin Beta-4 (Tβ4), a naturally occurring protein found in nearly all human and animal cells that plays a role in actin regulation, cell migration, and tissue repair. TB-500 is sold as a research chemical and is not an approved medicine.

Is TB-500 the same as Thymosin Beta-4?

They are closely related but not identical. Thymosin Beta-4 is the full 43-amino-acid natural protein. TB-500 typically refers to a synthetic peptide that contains the active actin-binding region of Tβ4. Marketing often uses the names interchangeably, which can be misleading.

What is TB-500 studied for?

Preclinical research on Thymosin Beta-4 and TB-500 has explored wound healing, muscle and tendon repair, corneal injury, and cardiac tissue protection after injury. This work is largely in animals and cells and does not establish human safety or efficacy.

Is TB-500 FDA-approved?

No. TB-500 is not approved by the FDA for any use. Thymosin Beta-4 has been investigated in some early clinical research, but TB-500 itself is sold only as a research chemical and is not a recognized therapy.

Is TB-500 banned in sports?

Yes. The World Anti-Doping Agency prohibits TB-500 and Thymosin Beta-4 in sport at all times under its growth factors and peptides category. Athletes subject to drug testing should avoid it.

What are the reported side effects of TB-500?

Human safety data are very limited. Anecdotal reports mention fatigue, lightheadedness, and injection-site reactions, but these are not well studied. Because long-term effects and interactions are unknown, consult a licensed clinician before considering it.

How is TB-500 reconstituted?

Lyophilized TB-500 powder is typically reconstituted with bacteriostatic water added slowly down the vial wall, then gently swirled until clear. See the steps below and our full reconstitution guide for details.

Healing & recovery · Dosage

TB-500 dosage

TB-500 comes in 10 mg vials. Pick your vial to see exactly how much bacteriostatic water to add and how many insulin units to draw. Reconstitution math and unit conversions for the 10 mg vial. TB-500 has no validated human dose; the usage patterns shown are community-reported and anecdotal.

10mg

At 2 mL water: 5 mg/mL
Per unit: 50 mcg

See the 10 mg card

Calculate for your vial

Enter the mg on your TB-500 vial, the bacteriostatic water you added, and your target dose — it works out the exact units to draw on a U-100 insulin syringe, for whatever you personally have.

Reconstitution Calculator

Units to draw (U-100)50units

Volume to draw0.5mL

Concentration5mg/mL

Per insulin unit50mcg

Doses per vial4doses

Check the decimal. A misplaced decimal point here is a 10× dosing error. Re-read every number, and confirm your dose with a licensed clinician before you draw.

Educational only — not a dosing recommendation. This tool does the measurement math; it does not tell you what to take. On a U-100 insulin syringe, 100 units = 1 mL.

Reconstitution figures are deterministic measurement math. WikiPeps is a community reference and sells injection supplies only — never peptides. Nothing here is medical advice.